Scleroderma, also known as Systemic Sclerosis or SSc, is an autoimmune disease that causes inflammation and fibrosis (thickening) in the skin and other areas of the body. It occurs when the immune system mistakenly triggers excess collagen production in healthy tissue, leading to the thickening and hardening of the skin.

This overproduction of collagen can affect areas such as the skin, heart, lungs, kidneys, and digestive tract, causing a loss of flexibility and proper function. As there is currently no cure, early diagnosis is critical in allowing for timely treatment, which can help relieve symptoms, stop disease progression, and improve quality of life.